This one-pan salmon and veggies makes one healthy, easy and tasty dinner. Salmon, butternut squash and brussels sprouts are coated in super easy homemade honey garlic sauce and baked together on a sheet pan for 30 minutes.

Love one-pan dishes? Then check out this sheet pan chicken and veggies and one pan chicken and potatoes! I even have air fryer salmon with veggies for even less clean up!

One pan salmon and veggies garnished with pepper

One Pan Salmon

In the last 3 weeks, we made this one pan salmon three times. I “borrowed” sauce recipe from my super popular honey garlic salmon one time and lime ginger salmon another. Most recently I tried it with this baked teriyaki salmon glaze.

Then I chose firm vegetables cut into similar size pieces to ensure veggies come out tender while salmon stays juicy.

Consistency throughout a sheet pan is key when it comes to one pan dinners.


We start with about 1.5 lbs salmon fillet. Preferably wild as science shows it is better for us and the environment.

When making one-pan dinner, it is important to pair wild salmon with vegetables that take same time to cook or cook veggies first. Because wild salmon is less fatty than farmed. It can come out dry if overcooked.


Cut vegetables into same size pieces. I do not peel brussels sprouts but rather just cut them in halves.

chopped brussels sprouts and butternut squash in separate bowls

To cut butternut squash, I first cut off a part without a hole. Then chop them separately into more or less even size cubes. It helps to peel an entire butternut squash and save some for later.

It refrigerates really well for up to a week. Then you can use the leftovers for sauteed butternut squash.

I like to make super simple butternut squash soup for lunch in my Blendtec. Or you can try my chicken butternut squash soup with Thai flavours. Mmmmmm.

butternut squash on a cutting board cut and peeled with a knife
cubed butternut squash on a cutting board

Honey Garlic Sauce

To make honey garlic sauce, we combine honey, lemon juice, fresh garlic, salt and pepper (I love this sauce so much I’ve even made baked honey garlic chicken). Give a whisk and use right away. Place salmon fillet in the middle of the baking sheet, pour 1/3 of honey garlic sauce on top and spread with a brush.

Then coat veggies in more sauce and a bit of oil so they roast nicely. Butternut squash first, then brussels sprouts. You can do it right on the pan but I like to dirty another bowl and just toss vegetables in there.

Transfer veggies as you are done seasoning them to a baking sheet. On one side of salmon fillet in a single layer. Repeat this step with brussels sprouts (I love parmesan roasted brussel sprouts!)

One pan salmon and veggies coated in honey garlic sauce on a baking sheet

How Long to Bake Salmon?

Bake one pan salmon and veggies for 30 minutes in 425 degrees oven with squash side further in the oven. It is the longest cooking vegetable on this tray that could benefit from more heat.

What to Serve One Pan Salmon and Veggies With?

This dinner is one pan meal on its own. If you want to make it a big meal for a crowd, below are a few ideas.

This salmon and butternut squash is perfect for meal prep. You could double the recipe!


One pan salmon

More Sheet Pan Dinner Recipes to Try

You might also enjoy this sweet chili salmon, grilled cedar plank salmon, grilled salmon, salmon stir fry, or simple canned salmon cakes.

One pan salmon with brussels sprouts and butternut squash on baking sheet.

One Pan Salmon and Veggies

One pan salmon and veggies coated in honey garlic sauce, then baked in a sheet pan for 30 minutes for a healthy easy dinner.
5 from 4 votes
Servings 6 servings
Calories 321
Prep Time 10 minutes
Cook Time 30 minutes


  • 1.5 lbs wild salmon fillet
  • 1.25 lbs butternut squash or 4 cups, cubed
  • 1.25 lbs brussels sprouts or 4 cups, halved
  • 2 tbsp avocado oil

Honey Garlic Sauce:


  • Preheat oven to 425 degrees F and line large baking sheet with silicone mat or unbleached parchment paper.
  • In a small bowl, add honey, lemon juice, garlic, salt, pepper and whisk.
  • Place salmon fillet in the middle of the baking sheet, pour 1/3 of honey garlic sauce on top and spread with a brush.
  • In a medium bowl, add butternut squash, drizzle with 1 tbsp oil and 1/3 of honey garlic sauce. Mix well to coat and transfer to a baking sheet on one side of salmon fillet in a single layer. Repeat this step with brussels sprouts.
  • Bake for 30 minutes with squash side further in the oven. Serve hot, with a side of quinoa if you wish. Perfect for a meal prep.



  • Store: Refrigerate in an airtight container for up to 5 days.


Calories: 321kcal | Carbohydrates: 29g | Protein: 27g | Fat: 12g | Saturated Fat: 2g | Cholesterol: 62mg | Sodium: 466mg | Fiber: 5g | Sugar: 13g
Course: Dinner
Cuisine: North American
Author: Olena Osipov
Did you make this recipe?Mention @ifoodreal or tag #ifoodreal!

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About Olena

Welcome! I grew up in Ukraine watching my grandma cook with simple ingredients. I have spent the last 11 years making it my mission to help you cook quick and easy meals for your family!

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  1. 5 stars
    Dear Miss Olena!!
    I loved your recipes, i loved your videos and they were perfect: informative, entertaining, and so professional. The time was great.. I too have the Instant pot and I really love cooking with it. I am making your chicken with potatoes and veggies today. And the salmon and veggies for my family tonight. I am using a less denser fish, though: talapia. So I think I will blanch my Brussels sprout a bit and cover the whole thing as well so it stays tender.

    Thank you for providing me with ideas!!
    In gratitude,
    Marky Mander
    Pipe Creek, Texas

    1. Awe, you are so welcome! So happy to hear you are enjoying my recipes! Please don’t be shy to leave me a comment with a star review once you make any recipe. Have a great weekend!

      1. I have piece of salmon that looks like yours in the picture but mine is frozen. I was hoping to use this recipe. Since you said no to using frozen salmon, what do you think would happen if I thawed this piece and used your recipe?

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